The Prime Minister of the Republic of Uzbekistan organizes and directs the activities of the Cabinet of Ministers, is personally responsible for its performance, preside at meetings of the Cabinet of Ministers, sign its decisions, the Cabinet of Ministers is in international relations and signed intergovernmental treaties and agreements, in consultation with the President of the Republic of Uzbekistan distributes responsibilities among the Deputy Prime Minister, decide on the governance and management, do not require consideration at a meeting of the Cabinet of Ministers, President of the Republic of Uzbekistan is making representation on the appointment and dismissal of khokims regions and Tashkent city, performs other functions provided by the laws of the Republic of Uzbekistan.

The candidature of the Prime Minister of the Republic of Uzbekistan offered a political party with the most seats in the elections to the Legislative Chamber of the Oliy Majlis, or more political parties have obtained an equal highest number of seats.

The President of the Republic of Uzbekistan, after considering the nominations for the post of Prime Minister within ten days of its offers for consideration and approval by the chambers of the Oliy Majlis.

A candidate for the post of the Prime Minister in the review and approval of the Oliy Majlis of the Republic of Uzbekistan is a program of action Cabinet of Ministers in the near and long term.

The candidature of the Prime Minister shall be deemed approved if it is filed for more than half of the votes of the total number of deputies of the Legislative Chamber, respectively, and the members of the Senate of Oliy Majlis of Uzbekistan.

Members of the Cabinet of Ministers approved by the President of the Republic of Uzbekistan for the Prime Minister.

In the event of a sustained conflict between the Prime Minister of the Republic of Uzbekistan and the Legislative Chamber of the Oliy Majlis on the proposal formally made in the name of the President of the Republic of Uzbekistan in the Legislative Chamber in the amount of not less than one third of the total, the question of the vote of no confidence to the Prime Minister submit for consideration by a joint session of the Oliy Majlis of Uzbekistan.

A vote of no confidence in the Prime Minister shall be considered adopted if it receives vote of at least two-thirds of the total, respectively, the Legislative Chamber and the Senate of Oliy Majlis of Uzbekistan. In this case, the President of the Republic of Uzbekistan shall decide on the dismissal of the Prime Minister from office. The entire composition of the Cabinet of Ministers resigns together with the Prime Minister.

A new candidate for the Prime Minister for consideration and approval by the chambers of the Oliy Majlis of Uzbekistan proposed to the President after consultation with all the political parties represented in the Legislative Chamber of Oliy Majlis of Uzbekistan.

In the case of a double rejection by the Oliy Majlis candidates for the post of the Prime Minister, the President of the Republic of Uzbekistan shall appoint an Acting Prime Minister and dissolve the Oliy Majlis of the Republic of Uzbekistan.

The Prime Minister on matters within its competence, issue orders.

The Prime Minister systematically inform the President of the Republic of Uzbekistan on the work of the Cabinet of Ministers.

In the absence of the Prime Minister shall act as a deputy prime minister.